Metabolism/ Metabolomics
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App. note 422: Distribution of Irinotecan in Liver and a HumanTumor Xenograft Model by Tissue Imaging Mass Spectrometry Author(s): Maria C. Prieto Conaway1, Shousong Cao2, Farukh Durrani2, Youcef Rustum2, Ping Wang3, Khin Marlar3, Latif Kazim3; 1 Thermo Fisher Scientific, San Jose, CA, USA; 2Roswell Park Cancer Institute, Dept. of Cancer Biology, Buffalo, NY, USA; 3 Roswell Park Cancer Institute, Dept. of Cell Stress Biology, Buffalo, NY, USA |
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App. note 420: Metabolomic Analysis of Green and Black Tea Extracts Using an LTQ Orbitrap XL Hybrid Linear Ion Trap Mass Spectrometer Author(s): Donna L. Wilson and Charles Yang; Thermo Fisher Scientific, San Jose, CA, USA |
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App. note 418: Re-interrogation of Verapamil Metabolites in Bile Using Time-based Data-dependent Mass Lists and a Mass Defect Filter with the LTQ Orbitrap Author(s): Laurance L. Lee1, Yan Chen1, Ji Ma2, Robert Cho2, Hoa Le2, Theresa McLaughlin3, and Shichang Miao4, 1Thermo Fisher Scientific, San Jose, CA; 2Amgen, South San Francisco, CA; 3Current Affiliation: Stanford University, Stanford, CA; 4Current Affiliation: Chemocentryx, Inc., Mountain View, CA |
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App. note 417: Using Multiple Mass Defect Filters and Higher Energy Collisional Dissociation on an LTQ Orbitrap XL for Fast, Sensitive and Accurate Metabolite ID Author(s): Yingying Huang1, Shirley Liu2, Shichang Miao2, Patrick M. Jeanville1, 1Thermo Fisher Scientific, San Jose, CA, USA; 2ChemoCentryx, Mountain View, CA, USA |
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App. Note 410: Rapid and Sensitive Analysis of Parent Drug and Metabolites Using FAIMS Separation in Combination with LC/MS Author(s): Julie A. Horner, Julian J. Phillips, and Patrick Jeanville, Thermo Fisher Scientific, San Jose, CA, USA |
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App. Note 406: Study of Free Radical Fragment Ions Generated from ESI-CID-MS/MS Using LTQ and LTQ Orbitrap Mass Spectrometers Author(s): Guifen Xu1, Tom Huang1, Jennifer Zhang2, Thomas D. McClure2, and Shichang Miao1 * 1 PKDM Department, Amgen SSF, South San Francisco, CA USA; *Analytical Chemistry and DMPK, ChemoCentryx Inc., Mountain View, CA USA; 2Thermo Fisher Scientific, San Jose, CA USA |
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App. note 415 Experimental Strategies for Determining the Distribution of Erlotinib in Pancreatic Tumors by MALDI Using an LTQ Linear Ion Trap Mass Spectrometer Author(s): M.C. Prieto Conaway1, H. Bui1, S. Beachy2, R. Pitoniak2, B. Hylander2, P.Wang2, K. Marlar2, E. Repasky2, L. Kazim2, 1Thermo Fisher Scientific, San Jose, CA, USA; 2Roswell Park Cancer Institute, Buffalo, NY, USA |
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App. note 413: The Distribution of Metabolites of Di-(2-ethylhexyl) Phthalate on a Whole Rat by Imaging MS Using a MALDI Ion Trap Author(s): T.A. Snow,1 M.Prieto Conaway,2 H. Bui,2 W.J.Fasano,1 L.A. Manning1, 1DuPont Haskell Laboratory, Newark, DE, USA; 2Thermo Fisher Scientific, San Jose, CA, USA |
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App. Note 392: Profiling and Characterization of Polyphenol Polymers from Cinnamon Using an Ion Trap Mass Spectrometer Author(s): Min He1, Peter Wang2, Ying Xiang3, Ying Qi3, Howard Sun3, and Julian Phillips1, 1Thermo Fisher Scientific, San Jose, CA, USA; 2Thermo Fisher Scientific, Shanghai, China; 3Shanghai R&D, Nu Sin Enterprises, Shanghai, China |
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App. Note 369: A High Throughput Approach for Metabolite Profiling and Characterization Using the LXQ Linear Ion Trap Mass Spectrometer Author(s): Min He, Alicia Du, Gargi Choudhary, Karen Salomon and Diane
Cho; Thermo Fisher Scientific, San Jose, CA, USA |
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App. Note 367: Essential Lipidomics Experiments Using the LTQ Orbitrap Hybrid Mass Spectrometer Author(s): Thomas Moehring1, Michaela Scigelova2, Christer S. Ejsing3, Dominik Schwudke3, Andrej Shevchenko3 1Thermo Fisher Scientific, Bremen, Germany; 2Thermo Fisher Scientific, Hemel Hempstead, UK; 3Max-Planck-Institute of Molecular Cell Biology and Genetics, Dresden, Germany |
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App. Note 359: Determination of Direct Glucuronidation of NCEs in Liver Microsomes Using SIM, Data Dependent Full-Scan MS/MS and CNL Scanning. Author(s): Veronique Van Genechten, Ethirajulu Kantharaj, Peter B Ehmer, Claire Mackie and Ron AHJ Gilissen; Department of ADME/Tox, In Vitro Pharmacokinetics Group, Johnson & Johnson Pharmaceutical Research & Development, 2340 Beerse, Belgium; Dipankar Ghosh, Louis Maljers and Karel Lazou; Thermo Fisher Scientific, San Jose, CA, USA |
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App. Note 350: Rapid Quantitative and Confirmational Screening for Drugs in Race Horse Urine by ESI-LC/MS/MS and MS/MS/MS. Author(s): Patrick Russell,1 Paul Steinberg,2 Mary L. Blackburn,2 Diane Cho,2 Robert Heather2 (1University of Florida, Racing Laboratory, Gainesville, Florida; 2Thermo Fisher Scientific, San Jose, California) |
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App. Note 349: Measurement of Metabolic Stability Using SIM and Identification of Metabolites by Data Dependent Full-Scan MS/MS and CNL Scanning Author(s): Peter B Ehmer, Ethirajulu Kantharaj, Katie De Wagter, Anne Van Vlaslaer, Claire Mackie and Ron AHJ Gilissen; Department of ADME/Tox, In Vitro Pharmacokinetics Group, Johnson & Johnson Pharmaceutical Research & Development, 2340 Beerse, Belgium; Dipankar Ghosh and Karel Lazou; Thermo Fisher Scientific, San Jose, CA, USA |
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App. Note 348: Identification of Phase I Biotransformation Products of Buspirone Using Parent Ion Scanning Triggered Data Dependent MS/MS Author(s): Kevin J. McHale, Scott M. Peterman and Mark R. Kagan; Thermo Fisher Scientific |
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App. Note 346: MS/MS as an LC Detector for the Screening of Drugs and Their Metabolites in Race Horse Urine. Author(s): Gargi Choudhary and Diane Cho, Thermo Fisher Scientific; Wayne Skinner and Scott Stanley, University of California–Davis |
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App. Note 334: Determination of Choline and Its Metabolites Using a LTQ Linear Ion Trap Mass Spectrometer. Author(s): Gargi Choudhary, Bradley Hart, and Diane Cho, Thermo Fisher Scientific, San Jose, California; Marie Caudill, Human Nutrition and Food Sciences, Cal Poly, Pomona, California |
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App. Note 312: Structural Determination of Flavonoids Using MSn. Author(s): Jack Cunniff, Philip Tiller, Michael Harvey, and Adrian Land, Thermo Fisher Scientific, San Jose, CA | Back to top |
